Endogenous endophthalmitis after routine dental cleaning.

to amikacin, while 100% of isolates were sensitive to clarithromycin. Clinical resolution of infection may not occur despite appropriate antibiotic therapy. Intravitreal clarithromycin has been reported to be nontoxic to rabbit eyes up to a dose of 1.0 mg; to our knowledge, the use of intravitreal clarithromycin in humans has not been reported. In summary, M chelonae is an uncommon cause of endophthalmitis. It is associated with a chronic course of marked intraocular inflammation and, in some cases, a white plaque inside the capsular bag in eyes after cataract surgery. While macrolide antibiotics may show good in vitro efficacy against M chelonae, endophthalmitis caused by this organism has generally poor visual acuity outcomes.